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Dermal Filler for Nasolabial Folds

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Nasolabial folds, the deep smile lines that run from the sides of the nose to the corners of the mouth, are one of the first signs of facial aging that clients notice. As we lose volume and collagen in the cheeks and midface, skin starts to sag and these lines deepen. No skincare routine can fully smooth them out on its own.

Dermal fillers for nasolabial folds work by restoring the volume underneath the crease rather than just filling the line itself, which is why an experienced injector with a solid knowledge of facial anatomy matters as much as the filler brand. At Aesthetics MedSpa, our RN-led injectors build a treatment plan around your anatomy so results look like a rested, refreshed version of you, not a different face.

What Causes Nasolabial Folds?

As we age, the fat pads in the cheeks and midface gradually shrink and shift downward, and the skin produces less collagen and elastin to keep it taut. That volume loss removes the support that once held the skin near the corners of the mouth in place, letting nasolabial folds and other fine lines settle in. Sun exposure, smoking, and years of repeated facial expressions add to the effect, and genetics play a role in how early and how deep they become.

Rapid weight loss can accelerate the same pattern. Clients using GLP-1 medications sometimes notice their smile lines deepen as facial fat decreases, a side effect commonly called “Ozempic face.” Filler is one of the most direct, minimally invasive ways to treat nasolabial folds, whatever is driving the volume loss.

Are Dermal Fillers Good for Nasolabial Folds?

Facial filler injections are considered one of the most effective, non-surgical ways to treat nasolabial folds, since they directly restore lost volume rather than just relaxing muscle movement. Benefits include:

Softens deep smile lines and restores volume lost to aging or weight loss
Results are visible immediately, with no incisions or plastic surgery required
Minimally invasive, with minor side effects and little downtime
Can stimulate collagen production over time, depending on the filler used
Customizable to your facial anatomy and how deep your folds have become
Can be paired with cheek or lip filler for a balanced, natural-looking contour

What Is the Best Filler for Nasolabial Folds?

The best filler for nasolabial folds depends on how deep your folds are, how your face moves, and how long you want results to last. Not every filler behaves the same way once it’s under the skin, and the nasolabial area flexes constantly with speech and expression, so your injector will recommend a formula built for that kind of movement.

RHA Fillers by Revance

Revance RHA fillers are made with Resilient Hyaluronic Acid, engineered to flex with the face rather than resist it. They’re FDA-approved specifically for dynamic wrinkles like nasolabial folds, which makes this filler line one of our most common recommendations for the area.

Restylane-L

Restylane-L is a hyaluronic acid filler calibrated for moderate to deep nasolabial folds and includes lidocaine at the injection site for a more comfortable experience. It’s a longstanding, well-studied choice for smoothing the nose-to-mouth crease.

Juvéderm Ultra Plus XC

Juvéderm Ultra Plus XC is formulated for deep nasolabial folds, with a denser gel that holds its contour well in an area that moves as much as this one does.

Nasolabial Fold Filler or Botox?

Botox relaxes the muscles that cause dynamic wrinkles, which is why it works well on lines like crow’s feet or the elevens between the brows. Nasolabial folds form mostly from volume loss and sagging skin, not repeated muscle movement, which is why filler, not Botox, is the standard treatment option for this area.

Some clients pair the two, using Botox for expression lines elsewhere and filler to treat nasolabial folds directly, but for the folds, a hyaluronic acid filler is almost always the right call.

What to Expect During Your Nasolabial Fold Filler Treatment

Most nasolabial fold filler appointments take 30 to 45 minutes from consultation through completion.

Your injector will first talk through your goals and assess how much volume loss is contributing to your folds. The injection site is numbed, and most fillers already contain lidocaine to make the injections more comfortable, whether your injector uses a fine needle or a cannula.

You’ll see results the same day, though mild bruising, swelling, or redness can linger for a day or two. Since filler gradually breaks down over time, most clients schedule a touch-up as results fade rather than waiting for severe nasolabial folds to fully return.

FAQ

Most frequent questions and answers

Are dermal fillers good for nasolabial folds?

Yes. Because nasolabial folds form mainly from volume loss and sagging skin rather than muscle movement, dermal fillers, which directly restore that lost volume, are considered one of the most effective non-surgical treatments available for this area.

How long will fillers last in nasolabial folds?

Most nasolabial fold fillers last 6 to 18 months, depending on the formula used and how quickly your body metabolizes hyaluronic acid. Denser fillers like Juvéderm Ultra Plus XC tend to last toward the longer end of that range, while lighter formulas may need a touch-up sooner.

How much does nasolabial fold filler cost?

Pricing depends on the filler brand and how many syringes it takes to reach your goals, since deep nasolabial folds generally need more product than early-stage lines. At your consultation, we’ll provide a clear, upfront quote before you commit to anything, and Cherry and CareCredit financing are available to spread the cost into manageable payments.

What is the best filler for nasolabial folds?

Hyaluronic acid fillers such as RHA, Restylane-L, and Juvéderm Ultra Plus XC are among the most commonly used fillers for nasolabial folds, since they’re formulated to move naturally with the face. The right choice depends on how deep your folds are and how long you want results to last, which your injector will assess at your consultation.

How painful is nasolabial filler?

Most clients describe brief discomfort rather than pain. The injection site is numbed beforehand, and most filler brands already contain lidocaine, so any bruising or tenderness is typically the main aftereffect rather than pain during the procedure.

Can nasolabial fold filler be dissolved if I don't like the results?

Yes. Hyaluronic acid fillers, including RHA, Restylane, and Juvéderm, can be dissolved with an enzyme called hyaluronidase if you’re unhappy with the results.